At the end of each stage in Super Mario Bros. you get 50 points for each unit of time that you have left on the clock when you finish a stage.
But, let's say that you go to your favorite X-4 stage (the big castles)
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You make your way to Bowser and bide your time a little bit (this works best if you're fiery and can get him out of the way)
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And then hit the axe then the timer hits 000 seconds.
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The result? When you visit the mushroom retainer the clock starts counting down from 999 time units back down to zero.
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Giving you 49950 points instead of whatever amount you would have had, had you just gone for it.
And this trick is arcade only, I'm afraid.